BrainCast | Technology

An in-depth report on individual brain health

BrainCast Brain Health Reports provide a comprehensive analysis of each advanced multi-modal MRI scan that we perform, focusing on quantitative brain measurements to evaluate brain health

T1-Weighted Analysis

BrainCast reports utilize T1-weighted MRI analysis to assess the volume and thickness of 84 distinct cortical and sub-cortical brain regions, providing a detailed insight into the structural health of the brain.

Diffusion-Weighted MRI

Our reports harness the power of diffusion-weighted MRI to evaluate microstructural alterations in white matter, in more than 70 white matter tracts.

Benchmarked Data

To ensure a comprehensive understanding of an individual's brain health, all quantitative data derived from the scans is benchmarked against normative data from 1000 age-matched individuals .

Measured insights into brain health

BrainCast Brain Health Reports present findings of our in-house analysis of T1-weighted MRI, T2-weighted FLAIR, diffusion-weighted MRI (DWI), and susceptibility-weighted imaging (SWI). The T1-weighted MRI analysis examines the volume and thickness of 84 cortical and sub-cortical brain regions. Diffusion-weighted MRI is used to quantify microstructural changes in the white matter. FLAIR MRI scans are used for lesion load mapping and identifying white matter hyperintensities. All quantitative data obtained from the individual’s scans is compared against benchmark normative data of 1000 individuals within a 10-year age range.

Executive Summary

The Executive Summary from BrainCast offers a concise overview of the brain's health, highlighting how many regions fall within the normal healthy range when compared to an age-matched sample of 1000 subjects. This summary provides a quick snapshot, enabling a comprehensive review of all tissue and measurement types, presenting an overarching view of the entire brain on just one page.

MRI Analysis Summary

This section provides an overview of the various MRI techniques used during the scan, summarising the main findings. It serves as a foundation for the subsequent detailed analyses, setting the context for more in-depth examination.

Cerebral Microbleeds

Cerebral microbleeds are tiny haemorrhages in the brain, often signifying underlying vascular issues or potential risk for more severe bleeding events. This section pinpoints and assesses the presence and implications of these microbleeds.

Grey Matter

Grey matter is a key component of the central nervous system, consisting mainly of neuronal cell bodies. This section evaluates the health, volume, and condition of the grey matter, which plays a crucial role in muscle control, sensory perception, and decision-making.

Ventricle Volumes

Ventricle Volumes: Ventricle volumes pertain to the measurement of the brain's ventricles, which are fluid-filled cavities. Quantifying these volumes is essential as abnormal sizes can indicate certain neurological conditions or diseases.

Iron Load Mapping

Iron Load Mapping: Iron load mapping is a technique used to assess the amount and distribution of iron within the brain. Excessive iron accumulation or irregular distribution can be indicative of various neurological disorders.

White Matter Lesions

White Matter Lesions: White matter lesions are abnormal changes in the white matter regions of the brain. This section identifies and evaluates the presence of these lesions, which can be indicative of diseases like multiple sclerosis or vascular issues.

White Matter Microstructure

White Matter Microstructure: This delves deeper into the white matter's intricate structure, assessing its health and integrity. White matter is essential for transmitting neural signals, and any microstructural changes can impact cognitive function and other neural processes.